The RENT1 Antibody (N-term E22) from MyBioSource.com is a Rabbit Polyclonal antibody to UPF1, and UPF1 RNA helicase and ATPase. This antibody recognizes Human antigen. The RENT1 Antibody (N-term E22) has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping