MyBioSource.com's MOUSE ANTI CAT MHC CLASS II is a Mouse monoclonal antibody. The MOUSE ANTI CAT MHC CLASS II Antibody was generated using HLA-DQB1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, and Western Blot.
Description
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region. MBS214486 recognises an epitope within the 29-31kDa beta chain region of cat MHC class II molecules which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes. The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV). Studies have shown that the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections