The ORAI1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ORAI1. This antibody recognizes Human, Mouse, and Rat antigen. The ORAI1 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1)