HCG-beta Antibody MBS438140 from MyBioSource.com

Product Specs
ItemHCG-beta Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438140
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesCGB8, CG-beta-a, CGB5, CGB6, CGB7, CGB3, hCGB
NCBI Full Gene Namechorionic gonadotropin, beta polypeptide, chorionic gonadotropin, beta polypeptide 7
ApplicationsWB, ELISA, IHC
ImmunogenThis MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior
HostMouse
CloneHCGb/459
Molecular Weight22kDa
IsotypeIgG1 kappa
TargetHCG-beta
Conjugate/TagUnconjugated
Quantity0.1 mg