The PPOX Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PPO, PPOX, and protoporphyrinogen oxidase. This antibody recognizes Human, Mouse, and Rat antigen. The PPOX Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified