The ADAM17 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ADAM17. This antibody recognizes Human, Mouse, and Rat antigen. The ADAM17 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway