The RAT ANTI MOUSE CD36:Low Endotoxin Antibody from MyBioSource.com is a Rat Monoclonal antibody to CD36. This antibody recognizes Mouse antigen. The RAT ANTI MOUSE CD36:Low Endotoxin Antibody has been shown to work in the following applications: Flow Cytometry, Functional Assay, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
Rat anti Mouse CD36 antibody, clone MF3 recognizes mouse CD36, an 85kD transmembrane glycoprotein which is primarily expressed on platelets, monocytes/macrophages, smooth muscle and endothelial cells. The CD36 molecule is type B scavenger receptor, which binds to multiple ligands including thrombospondin, anionic phospholipids, oxidized low density lipoproteins and long chain fatty acids. CD36 has diverse functions and is reported to play a role in innate immunity, platelet adhesion/aggregation and long chain fatty acid transport. The CD36 molecule also directly mediates cytoadhesion of erythrocytes infected with Plasmodium falciparum, and may be involved in the development of atherosclerotic lesions and the formation of foam cells. Rat anti Mouse CD36 antibody, clone MF3 has been shown to inhibit IL-4 induced thioglycollate-elicited peritoneal macrophage fusion and significantly block IL-4/GM-CSF-induced bone-marrorw derived macrophage fusion