MyBioSource.com's RAD51C Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RAD51C Antibody (Center) was generated using RAD51C as the antigen and it reacts with Human.
Description
This gene is a member of the RAD51 family of related
genes, which encode strand-transfer proteins thought to be involved
in recombinational repair of damaged DNA and in meiotic
recombination. This gene product interacts with two other DNA
repair proteins, encoded by RAD51B and XRCC3, but not with itself.
The protein copurifies with XRCC3 protein in a complex, reflecting
their endogenous association and suggesting a cooperative role
during recombinational repair. This gene is one of four localized
to a region of chromosome 17q23 where amplification occurs
frequently in breast tumors. Overexpression of the four genes
during amplification has been observed and suggests a possible role
in tumor progression. Alternative splicing has been observed for
this gene and two variants encoding different isoforms have been
identified