The PFN2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PFN2, and profilin 2. This antibody recognizes Human, Mouse, and Rat antigen. The PFN2 Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG