MyBioSource.com's ADAM10 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Immunohistochemistry. The ADAM10 Polyclonal Antibody was generated using ADAM10, kuz, and Kuzbanian as the antigen and it reacts with Human, Mouse, and Rat.
Description
This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. Sheddase, a generic name for the ADAM metallopeptidase, functions primarily to cleave membrane proteins at the cellular surface. Once cleaved, the sheddases release soluble ectodomains with an altered location and function