Mouse Anti-Chicken CD8a-CY5 MBS673874 from MyBioSource.com

Product Specs
ItemMouse Anti-Chicken CD8a-CY5
CompanyMyBioSource.com
Price $375.00Supplier Page View Company Product Page
Catalog NumberMBS673874
Quantity0.1 mg
ApplicationsFlow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation
Conjugate/TagCyanine 5 (CY5)
FormatCyanine 5 (CY5) Conjugate
ReactivityChicken
TargetCD8 alpha
IsotypeIgG1 kappa
Molecular Weight24,017 Da
CloneCT-8
HostMouse
Antibody TypeSecondary
Immunogenalpha chain (34-kDa) of chicken CD8
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.1,3 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1,2 MAb CT-8 recognizes the CD8 alpha chain.1
NCBI Full Gene NameCD8a molecule
NCBI Gene Aliaseszgc:136643
ClonalityMonoclonal