The CASP6 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP6. This antibody recognizes Human, Mouse, and Rat antigen. The CASP6 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms