MyBioSource.com's RAT ANTI HUMAN CD52 Antibody is a Rat monoclonal antibody. The RAT ANTI HUMAN CD52 Antibody was generated using CD52 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Assay, Flow Cytometry, Functional Assay, Immunohistochemistry, and Western Blot.
Description
MBS216359 reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29kDa. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies