Actin, Smooth Muscle MBS438497 from MyBioSource.com

Product Specs
ItemActin, Smooth Muscle
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438497
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman, Baboon, Monkey, Cow, Pig, Sheep, Goat, Cat, Dog, Rabbit, Mouse, Rat, Guinea pig, Chicken
TargetActin
IsotypeIgG2a kappa
Molecular Weight42kDa
Clone1A4; same as asm-1
HostMouse
ImmunogenActin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin
NCBI Full Gene Nameactin, alpha 2, smooth muscle, aorta
NCBI Gene AliasesACTSA, MYMY5, AAT6
ClonalityMonoclonal