The ACMSD Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ACMSD. This antibody recognizes Human, Mouse, and Rat antigen. The ACMSD Polyclonal Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4. 1. 1. 45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS