CD31/ PECAM-1 Antibody MBS438463 from MyBioSource.com

Product Specs
ItemCD31/ PECAM-1 Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438463
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesCD31/EndoCAM, PECAM-1, CD31, PECA1, GPIIA', endoCAM
NCBI Full Gene Nameplatelet/endothelial cell adhesion molecule 1
ApplicationsWB, ELISA, FCM, IF, IHC, IP
ImmunogenCD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence
HostMouse
CloneC31.3
Molecular Weight~100kDa (endothelium); ~130kDa (platelets)
IsotypeIgG1 kappa
TargetCD31
Conjugate/TagUnconjugated
Quantity0.1 mg