The CFL2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CFL2, and Cofilin 2. This antibody recognizes Human, Mouse, and Rat antigen. The CFL2 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants