MyBioSource.com's TCEB2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The TCEB2 Antibody (Center) was generated using elongin b as the antigen and it reacts with Human.
Description
This gene encodes the protein elongin B, which is a
subunit of the transcription factor B (SIII) complex. The SIII
complex is composed of elongins A/A2, B and C. It activates
elongation by RNA polymerase II by suppressing transient pausing of
the polymerase at many sites within transcription units. Elongin A
functions as the transcriptionally active component of the SIII
complex, whereas elongins B and C are regulatory subunits. Elongin
A2 is specifically expressed in the testis, and capable of forming
a stable complex with elongins B and C. The von Hippel-Lindau tumor
suppressor protein binds to elongins B and C, and thereby inhibits
transcription elongation. Two alternatively spliced transcript
variants encoding different isoforms have been described for this
gene. Pseudogenes have been identified on chromosomes 11 and 13