The PFKP Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PFKF, PFKP, and phosphofructokinase, platelet. This antibody recognizes Human, Mouse, and Rat antigen. The PFKP Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2. 7. 1. 11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1, 6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2