MyBioSource.com's POU3F2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The POU3F2 Antibody (Center) was generated using BRN2, and POU3F2 as the antigen and it reacts with Human, and Rat.
Description
POU3F2 belongs to a large family of transcription factors
that bind to the octameric DNA sequence ATGCAAAT. Most of these
proteins share a highly homologous region, referred to as the POU
domain, that occurs in several mammalian transcription factors,
including the octamer-binding proteins Oct1 (POU2F1; MIM 164175)
and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1;
MIM 173110). Class III POU genes are expressed predominantly in the
central nervous system (CNS). It is likely that CNS-specific
transcription factors such as these play an important role in
mammalian neurogenesis by regulating their diverse patterns of gene
[removed]Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et
al., 1995 [PubMed 7601453])