The RAT ANTI MOUSE TNF ALPHA Antibody from MyBioSource.com is a Rat Monoclonal antibody to DIF, TNF, TNFa, TNFalpha, and Tumor necrosis factor. This antibody recognizes Mouse, and Rat antigen. The RAT ANTI MOUSE TNF ALPHA Antibody has been shown to work in the following applications: ELISA, Flow Cytometry, and Immunohistochemistry.
Description
Rat anti Mouse TNF alpha antibody, clone MP6-XT22 recognizes mouse tumor necrosis factor alpha (TNF alpha), a ~17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immuno-regulatory role. Rat anti Mouse TNF alpha antibody, clone MP6-XT22 is reported to neutralize the effects of mouse TNF alpha (Gaup et al. 2008 and Yang et al. 1995)