The MMP2 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to CLG4A, GelA, MMP2, and TBE-1. This antibody recognizes Human, Mouse, Rat, and Rabbit antigen. The MMP2 Antibody (Center) has been shown to work in the following applications: ELISA, and Western Blot.
Description
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. This gene encodes an enzyme which
degrades type IV collagen, the major structural component of
basement membranes. The enzyme plays a role in endometrial
menstrual breakdown, regulation of vascularization and the
inflammatory response. Mutations in this gene have been associated
with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO)
syndrome. Two transcript variants encoding different isoforms have
been found for this gene