MyBioSource.com's MOUSE ANTI PCNA Antibody is a Mouse monoclonal antibody. The MOUSE ANTI PCNA Antibody was generated using PCNA, PCNAR, and proliferating cell nuclear antigen as the antigen. It reacts with Human, Mouse, Rat, Amoeba/Protozoa, Bacteria/Archaea, Bovine, C. elegans/Worm, Canine, Chicken/Bird, Donkey, Drosophila/Arthropod, Feline, Goat, Guinea Pig, Hamster, Horse, Mollusc, Non-Human Primate, Porcine, Reptile, Rabbit, Sheep, Xenopus/Amphibian, Yeast/Fungi, Zebrafish/Fish, Other Invertebrate, and Other Mammalian. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Mouse anti PCNA antibody, clone PC10 recognises the proliferating cell nuclear antigen, also known as PCNA or cyclin, PCNA is a 261 amino acid ~28kDa nuclear protein vital for cellular DNA synthesis at the replication fork (Li et al. 1995) through it's interaction with FEN1 (Wu et al. 1996). PCNA is the auxilliary protein for DNA polymerase delta (Bravo et al. 1987). PCNA is highly conserved between mammalian species and other vertebrates. Mouse anti Human PCNA, clone PC10 has been used for the detection of PCNA in a number of species including rat (Elsässer et al. 1994), mouse (Park et al. 2008), chicken (Franz-Odendaal 2008) and abalone (Harris et al. 2006)