The Phospho-RPS6KB1 (S418) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to p70 S6k1, p70 S6KA, p70S6K, p70S6K1, RPS6KB1, S6K, and S6K1. This antibody recognizes Human, Mouse, Rat, and Rabbit antigen. The Phospho-RPS6KB1 (S418) Antibody has been shown to work in the following applications: Dot Blot, and ELISA.
Description
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized