The SPR Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Sepiapterin Reductase, and SPR. This antibody recognizes Human, Mouse, and Rat antigen. The SPR Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1