The TSLP Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Thymic Stromal Lymphopoietin, and TSLP. This antibody recognizes Human, Mouse, and Rat antigen. The TSLP Polyclonal Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants