CEA Antibody MBS438510 from MyBioSource.com

Product Specs
ItemCEA Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438510
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman
TargetCEA
IsotypeIgG2a kappa
Molecular Weight80-200kDa
CloneCOL-1
HostMouse
ImmunogenThis antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix
NCBI Full Gene Namecarcinoembryonic antigen-related cell adhesion molecule 5
NCBI Gene AliasesCEA, CD66e
ClonalityMonoclonal