MyBioSource.com's LGR5/GPR49 Antibody (loop2) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunofluorescence, and Western Blot. The LGR5/GPR49 Antibody (loop2) was generated using FEX, and GRP49 as the antigen and it reacts with Human, Mouse, and Rat.
Description
LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region
of brain. Expressed at the base of crypts in colonic and small mucosa
stem cells. In premalignant cancer expression is not restricted to the
cript base. Overexpressed in cancers of the ovary, colon and liver