The RAPGEF5 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to RAPGEF5. This antibody recognizes Human antigen. The RAPGEF5 Antibody (C-term) has been shown to work in the following applications: ELISA, and Western Blot.
Description
Members of the RAS (see HRAS; MIM 190020) subfamily of
GTPases function in signal transduction as GTP/GDP-regulated
switches that cycle between inactive GDP- and active GTP-bound
states. Guanine nucleotide exchange factors (GEFs), such as
RAPGEF5, serve as RAS activators by promoting acquisition of GTP to
maintain the active GTP-bound state and are the key link between
cell surface receptors and RAS activation (Rebhun et al., 2000
[PubMed 10934204])