MyBioSource.com's Mouse Anti Human STAT1 is a Mouse monoclonal antibody. The Mouse Anti Human STAT1 Antibody was generated using STAT1 as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
Introduction: STAT1 is a member of the Signal Transducers and Activators of Transcriptionfamily of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type Ior type IIinterferons. In response to IFN-?stimulation, STAT1 forms homodimers or heterodimers with STAT3that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element; in response to either IFN-? or IFN-?stimulation, STAT1 forms a heterodimer with STAT2that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case, binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes)