MyBioSource.com's STC2 Antibody is a Mouse monoclonal antibody. The STC2 Antibody was generated using Stanniocalcin 2, and STC2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
This gene encodes a secreted, homodimeric glycoprotein
that is expressed in a wide variety of tissues and may have
autocrine or paracrine functions. The encoded protein has 10 of its
15 cysteine residues conserved among stanniocalcin family members
and is phosphorylated by casein kinase 2 exclusively on its serine
residues. Its C-terminus contains a cluster of histidine residues
which may interact with metal ions. The protein may play a role in
the regulation of renal and intestinal calcium and phosphate
transport, cell metabolism, or cellular calcium/phosphate
homeostasis. Constitutive overexpression of human stanniocalcin 2
in mice resulted in pre- and postnatal growth restriction, reduced
bone and skeletal muscle growth, and organomegaly. Expression of
this gene is induced by estrogen and altered in some breast
cancers