CD104 (Integrin Beta-4) MBS438251 from MyBioSource.com

Product Specs
ItemCD104 (Integrin Beta-4)
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438251
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesCD104
NCBI Full Gene Nameintegrin, beta 4
ApplicationsWB, ELISA, FCM, IF, IHC, IP, BL
ImmunogenRecognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene
HostMouse
CloneUM-A9
Molecular Weight205kDa
IsotypeIgG2a kappa
TargetCD104
Conjugate/TagUnconjugated
Quantity0.1 mg