MyBioSource.com's PCGF2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PCGF2 Antibody (Center) was generated using PCGF2 as the antigen and it reacts with Human.
Description
The protein encoded by this gene contains a RING finger
motif and is similar to the polycomb group (PcG) gene products. PcG
gene products form complexes via protein-protein interaction and
maintain the transcription repression of genes involved in
embryogenesis, cell cycles, and tumorigenesis. This protein was
shown to act as a negative regulator of transcription and has tumor
suppressor activity. The expression of this gene was detected in
various tumor cells, but is limited in neural organs in normal
tissues. Knockout studies in mice suggested that this protein may
negatively regulate the expression of different cytokines,
chemokines, and chemokine receptors, and thus plays an important
role in lymphocyte differentiation and migration, as well as in
immune responses