MyBioSource.com's RAD23B Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RAD23B Antibody (N-term) was generated using RAD23B as the antigen and it reacts with Human, Mouse, and Rat.
Description
The protein encoded by this gene is one of two human
homologs of Saccharomyces cerevisiae Rad23, a protein involved in
the nucleotide excision repair (NER). This protein was found to be
a component of the protein complex that specifically complements
the NER defect of xeroderma pigmentosum group C (XP-c) cell
extracts in vitro. This protein was also shown to interact with,
and elevate the nucleotide excision activity of 3-methyladenine-DNA
glycosylase (MPG), which suggested a role in DNA damage recognition
in base excision repair. This protein contains an N-terminal
ubiquitin-like domain, which was reported to interact with 26S
proteasome, and thus this protein may be involved in the ubiquitin
mediated proteolytic pathway in cells