The FZD8 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to FZd8. This antibody recognizes Human, Mouse, and Rat antigen. The FZD8 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined