CD1a Antibody MBS438309 from MyBioSource.com

Product Specs
ItemCD1a Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438309
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesR4, FCB6, HTA1, T6, CD1
NCBI Full Gene NameCD1a molecule
ApplicationsWB, ELISA, FCM, IF, IHC, IP
ImmunogenAt least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa)
HostMouse
CloneO10
Molecular Weight49kDa
IsotypeIgG1 kappa
TargetCD1a
Conjugate/TagUnconjugated
Quantity0.1 mg