CD45RA Antibody MBS438154 from MyBioSource.com

Product Specs
ItemCD45RA Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438154
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesLY5, GP180, CD45, L-CA, CD45R, LCA, T200, B220
NCBI Full Gene Nameprotein tyrosine phosphatase, receptor type, C
ApplicationsWB, ELISA, FCM, IF, IHC, IP
ImmunogenRecognizes a protein of 205kDa-220kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve)
HostMouse
Clone158-4D3
Molecular Weight205-220kDa
IsotypeIgG2a kappa
TargetCD45RA
Conjugate/TagUnconjugated
Quantity0.1 mg