MyBioSource.com's RNF14 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The RNF14 Antibody (C-term) was generated using RNF14 as the antigen and it reacts with Human.
Description
The protein encoded by this gene contains a RING zinc
finger, a motif known to be involved in protein-protein
interactions. This protein interacts with androgen receptor (AR)
and may function as a coactivator that induces AR target gene
expression in prostate. A dominant negative mutant of this gene has
been demonstrated to inhibit the AR-mediated growth of prostate
cancer. This protein also interacts with class III
ubiquitin-conjugating enzymes (E2s) and may act as a
ubiquitin-ligase (E3) in the ubiquitination of certain nuclear
proteins. Five alternatively spliced transcript variants encoding
two distinct isoforms have been reported