The Dnmt3a Antibody (N-term R46) from MyBioSource.com is a Rabbit Polyclonal antibody to DNMT3A, and DNMT3A2. This antibody recognizes Human, and Rat antigen. The Dnmt3a Antibody (N-term R46) has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated