Brilliant Violet 421™ anti-human CD4 344631 from BioLegend

Product Specs
ItemBrilliant Violet 421™ anti-human CD4
CompanyBioLegend
Price $191.00Supplier Page View Company Product Page
Catalog Number344631
Quantity25 tests
ApplicationsFC - Quality tested
Conjugate/TagBrilliant Violet 421™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityHuman
IsotypeMouse IgG1, kappa
CloneSK3
HostMouse
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
TargetCD4
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicityMolecular Therapy OncologySeptember 17, 2026Frederic St-Denis-Bissonnette, Karan Mediratta, Nicholas Ho, Melanie Kirkby, Andrew Stalker, Gauri Muradia, Amit Shrestha, Michele Ardolino, Seung-Hwan Lee, Dylan Burger, et al.titrated antibodies solution containing CD3-AF700 (BD Biosciences, cat#557917), CD4-BV421 (BioLegend, cat#344632), CD8-PE-Cy7 (BD Biosciences, cat#560917), CD14-BV510 (BD Biosciences, cat#740163), CD16-BV711 (BioLegend,

(2) Debio 1562M CD37-targeting ADC is highly active and well tolerated in preclinical models of AML and MDSCell Reports MedicineMay 19, 2026Léo Marx, Josée Hue-Perron, Alain Monjardet, Selena Vigano, Christophe Chardonnens, Kaitlin Morse, Esthela Artiga, Marie-Claude Roubaudi-Fraschini, René Wuttke, Riccardo Colombo, et al.Research,AB_2337651 CD45-FITC,BioLegend,"Cat# 310205, RRID:AB_2687313" anti-CD4-BV-421,BioLegend,"Cat# 344631, RRID:AB_2566014" anti-CD14-PerCP-Cy5.5,BioLegend,"Cat# 367109, RRID:AB_2566711" anti-CD16-PE,BioLegend,"Cat#

(3) Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritisTheranosticsJanuary 1, 2026Jong Yeong Lee, Jun Young Park, In Ah Kwon, Su Hyun Lim, Ki Bum Kim, Jun-Young Park, Youn Joo Kang, Sang-Hyun Kim, Dongwoo Khang, Jin Kyeong Choing mL⁻¹ PMA, 1 μg mL⁻¹ ionomycin, and Golgi plug for 4 h, followed by staining with anti-human CD4 (344632; BioLegend), CD73 (561558; BD Biosciences), IFN-γ (560742; BD Biosciences), TNF-α (557647; BD Biosciences),

(4) Single-cell transcriptomic profiling reveals aberrant CD4⁺ naive T cell differentiation driving immune activation in Behçet’s uveitisJournal of Translational MedicineDecember 2, 2025Lu Zhang, Yimeng Sun, Xinyu Yao, Chun Yan, Yunfei Liu, Dijie Qiao, Ziyu Du, Cong Hu, Fuying Guo, Ziwei Meng, et al.intracellular cytokine staining, cells were first surface-stained with anti-human CD4 antibody (BioLegend, Cat# 344632) at 4 °C for 30 min in the dark, followed by fixation and permeabilization. Cells were then stained

(5) iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumorsCell Reports MedicineJuly 15, 2025Bi-Huei Yang, Alma Gutierrez, Angela Liao, Soheila Shirinbak, Bjoern Gaertner, Mochtar Pribadi, Hui-Yi Chu, Pei-Fang Tsai, Yu-Sheng Eason Lin, David Gonzalez, et al.anti-human CD7 (BD Bioscience, 555361), anti-human CD5 (BD Bioscience, 555352), anti-human CD4 (BioLegend, 344631), anti-human CD8a (BD Bioscience, 612754), anti-human CD62L (BD Bioscience, 559772), anti-human CD45RA

(6) ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2Biomark ResJanuary 23, 2025Dan Li, Wenjie Zhang, Ruiheng Wang, Shufeng Xie, Yixin Wang, Wanxin Guo, Zixuan Huang, Chaoqun Lu, Liang Shan, Han Liu, et al.follows: PE/Cyanine5 anti-human CD3 (Biolegend, 317356), Brilliant Violet 421 anti-human CD4 (Biolegend, 344632), Brilliant Violet 510 anti-human CD8 (Biolegend, 344732), APC anti-human CD69 (Biolegend, 310910),

(7) Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural NetworkJournal of Molecular BiologyJanuary 15, 2025Claire H. Woodward, Shahlo O. Solieva, Daniel Hwang, Viviane S. De Paula, Charina S. Fabilane, Michael C. Young, Tony Trent, Ella C. Teeley, Ananya Majumdar, Jamie B. Spangler, et al.following antibodies: CD3 FITC (UCHT1, BioLegend 300406, 0.2 test volume/well), CD4 BV421 (SK3 BioLegend 344632, 0.2 test volume/well), CD8 BV605 (SK1 BioLegend 344742, 0.2 test volume/well). Cells were incubated

(8) Single-cell atlas reveals a distinct immune profile fostered by T cell-B cell crosstalk in triple negative breast cancerCancer communications (London, England)June 1, 2023Ding S, Qiao N, Zhu Q, Tong Y, Wang S, Chen X, Tian Q, Xiao Y, Shen K.Violet 421, 562444, 1: 200), anti‐human CD3 (PE, 317307, 1: 200), anti‐human CD4 (Brilliant Violet 421, 344632, 1: 200), anti‐human CD8 (Brilliant Violet 510, 344732, 1: 200), anti‐human CD25 (FITC, 302603, 1: 200),

(9) Identification and Isolation of Type II NKT Cell Subsets in Human Blood and LiverFrontiers in immunologyJanuary 1, 2022Yang Zhou J, Werner JM, Glehr G, Geissler EK, Hutchinson JA, Kronenberg K.BioLegend), αCD56 APC (318310, BioLegend), αCD3 APC-H7 (560176, BD Biosciences, USA) and αCD4 BV421 (344632, BioLegend) in a final volume of 100 µl/sample comprising CSB plus 50 µl Brilliant Staining Buffer (563794,

(10) Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian CancerCancer immunology researchJuly 1, 2021Emmons TR, Giridharan T, Singel KL, Khan ANH, Ricciuti J, Howard K, Silva-Del Toro SL, Debreceni IL, Aarts CEM, Brouwer MC, et al.with antibodies specific for CD15 (clone HI98; cat. #563872, BD Biosciences), CD4 (clone SK3; cat. #344632, Biolegend), and CD8 (clone SK1; cat. #344714, Biolegend) followed by fixation, permeabilization and

(11) Multimodal analysis for human ex vivo studies shows extensive molecular changes from delays in blood processingiScienceMay 21, 2021Savage AK, Gutschow MV, Chiang T, Henderson K, Green R, Chaudhari M, Swanson E, Heubeck AT, Kondza N, Burley KC, et al.RRID:AB_396152 CD38 APC (HB-7),BioLegend,Cat#356606; RRID:AB_2561902 CD4 BV421 (SK3),BioLegend,Cat#344632; RRID:AB_2566015 CD4 BV480 (SK3),BD,Cat#566104; RRID:AB_2739506 CD45 BUV496 (HI30),BD,Cat#750179;

(12) Distinct microbial and immune niches of the human colonNature immunologyMarch 1, 2020James KR, Gomes T, Elmentaite R, Kumar N, Gulliver EL, King HW, Stares MD, Bareham BR, Ferdinand JR, Petrova VN, et al.CD3-FITC (clone OKT3; Biolegend, cat. 317305; dilution 1:100), CD4-BV421 (clone SK3; Biolegend, cat. 344631; dilution 1:100), CD8-PE-Cy7 (clone SK1, Biolegend, cat. 344711; dilution 1:100), CD19-APC-Cy7 (clone

(13) Human CD4+ lymphocytes for antigen quantification: characterization using conventional flow cytometry and mass cytometryCytometry. Part A : the journal of the International Society for Analytical CytologyJuly 1, 2012Wang L, Abbasi F, Ornatsky O, Cole KD, Misakian M, Gaigalas AK, He HJ, Marti GE, Tanner S, Stebbings R.

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Brilliant Violet 421™ anti-human CD4 from BioLegend

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Brilliant Violet 421™ anti-human CD4 from BioLegend

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