The Lambda Light Chain Antibody Cocktail from Biorbyt is a Mouse Monoclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The Lambda Light Chain Antibody Cocktail has been shown to work in the following applications: Cell Sorting, Isolation, Flow Cytometry, Immunofluorescence, and Western Blot.
Description
This antibody cocktail is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Lambda light chain antibody is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant