The rSec6 Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Hamster, Non-Human Primate, Porcine, Rabbit, and Sheep antigen. The rSec6 Antibody has been shown to work in the following applications: Immunocytochemistry, and Western Blot.
Description
rSec6 is an 87kD rat homolog of yeast Sec6p, a protein involved in protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec6p is part of a high molecular weight complex which includes Sec8p and Sec15p, that associates with the ras-like GTP binding protein Sec4p. An analogous 17S complex in rat brain was found to contain eight novel proteins, including rSec6 and rSec8, with a combined molecular weight of 734kD. Membrane-associated rSec6/8 complex has been shown to co-immunoprecipitate with syntaxin, and is ubiquitously expressed, further evidence that this complex is involved in the mammalian exocyst complex