The LNX1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to LNX, LNX1, MPDZ, and MUPP1. This antibody recognizes Human antigen. The LNX1 Antibody has been shown to work in the following applications: Western Blot.
Description
LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65