The IL2RB Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD122, IL15RB, and IL2RB. This antibody recognizes Human antigen. The IL2RB Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein