The FBXW7 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Ago, Cdc4, FBW7, and FBXW7. This antibody recognizes Human antigen. The FBXW7 Antibody has been shown to work in the following applications: Western Blot.
Description
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1