The GLRX Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to glrx, Glutaredoxin, GRX, and GRX1. This antibody recognizes Human, Mouse, and Rat antigen. The GLRX Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified