Ganglioside GD2 (Disialoganglioside GD2) Antibody MBS601247 from MyBioSource.com

Description

GD2 has been identified as tumor-associated antigens expressed on the surface of neuroectoderm-derived tumors (melanoma, neuroblastoma and glioma) and T-cell leukemia. Gangliosides (sialic acid-containing glycosphingolipids) are normal membrane constituents and highly expressed in the vertebral central nervous system

Product Specs
ItemGanglioside GD2 (Disialoganglioside GD2) Antibody
CompanyMyBioSource.com
Price $790.00Supplier Page View Company Product Page
Catalog NumberMBS601247
Quantity0.1 mg
ApplicationsImmunofluorescence, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Cytoxicity
Conjugate/TagUnconjugated
FormatSupplied as a liquid in PBS, pH 7.6, 0.09% sodium azide
PurityPurified by Protein A affinity chromotography from ascites
ReactivityHuman
TargetGanglioside GD2
IsotypeIgG2a
Clone2Q549
HostMouse
ImmunogenRecognizes human GD2 ganglioside
ClonalityMonoclonal
Concentration1 mg/mL

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Questions and Answers

What types of tumors can this antibody be used to study?

The Ganglioside GD2 antibody is particularly relevant for research on neuroectoderm-derived tumors, including melanoma, neuroblastoma, and glioma, as well as T-cell leukemia, due to the expression of GD2 as a tumor-associated antigen on these cells.

Can this antibody be used for flow cytometry applications?

Yes, the Ganglioside GD2 antibody has been shown to be applicable for flow cytometry, allowing for the analysis of GD2 expression on the surface of relevant tumor cells.

Is this antibody suitable for immunohistochemistry?

The Ganglioside GD2 antibody is suitable for immunohistochemistry, which can be utilized to visualize GD2 expression in tissue sections, providing insights into tumor biology and potential therapeutic targets.

What is the host species for this antibody, and how does that affect its use in experiments?

This antibody is derived from a mouse host species, which is important to consider when selecting secondary antibodies for detection, as mouse IgG2a isotype-specific secondary antibodies will be required for optimal results in various applications.