MyBioSource.com's Endoplasmic Reticulum-associated Amyloid Beta-peptide binding protein (ERAB) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot. The Endoplasmic Reticulum-associated Amyloid Beta-peptide binding protein (ERAB) Antibody was generated using HSD17B10 as the antigen and it reacts with Human.
Description
Endoplasmic reticulum-associated amyloid beta-peptide binding protein (ERAB) is a 27kD protein, member of the short-chain dehydrogenase/reductase family, it catalyses the oxidation of a wide variety of fatty acids, alcohols, and steroids. It is constitutively expressed in tissues and overexpressed in neurons affeceted in Alzheimer's disease. ERAB binds amyloid.beta and may be a determining factor in the level of cytotoxicity observed in the brain of Alzheimer's patients