The Complement Factor H-Related Protein 1 (FHR1) Antibody from MyBioSource.com is a Sheep Polyclonal antibody to CFHR1. This antibody recognizes Human antigen. The Complement Factor H-Related Protein 1 (FHR1) Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunoprecipitation, and Western Blot.
Description
Complement Factor H-related protein 1 is a 43kD, secreted member of the factor H family of glycoproteins. It is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37kD and 43kD). Mature human FHR1 is 312aa in length. It contains five, ~60aa SCRs (short consensus repeats/CCPs/SUSHI repeats) that basically constitute the entire molecule. FHR1 may play a role in lipoprotein complexes that bind PMNs to LPS. There is no reported rodent counterpart to FHR1. Over aa 19-143 of the FHR1 precursor, human FHR2 and FHR5 show 98% and 86% aa identity, respectively