The ADAMTSL2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ADAMTS like 2, ADAMTSL2, and Miscellaneous. This antibody recognizes Human, Mouse, and Rat antigen. The ADAMTSL2 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia